学术论文_科研成果_最新资讯

2024-09

11

Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases

Inherited retinal diseases (IRDs) can induce severe sight-threatening retinal de...
2024-09

05

Development of injectable hyaluronic acid-based hydrogelswith antioxidant activity for the treatment of corneal neovascularization

Corneal neovascularization (CNV) is a condition that can severely adversely affe...
2024-09

04

Diabetes Reshapes the Circadian Transcriptome Profile in Murine Retina

Diabetic retinopathy (DR) is a common complication of diabetes and has a high pr...
2024-09

04

Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids

Diabetic retinopathy (DR) development is associated with disturbances in the gut...
2024-09

04

One-Stop Assembly of Adherent 3D Retinal Organoids from hiPSCs based on 3D-printed derived PDMS Microwell Platform

The three-dimensional (3D) retinal organoids (ROs) derived from human induced pl...
2024-09

04

Microneedles for in situ tissue regeneration

Tissue injury is a common clinical problem, which may cause great burden on pati...
2024-09

04

LM22B-10 promotes corneal nerve regeneration through in vitro 3D co-culture model and in vivo corneal injury model

Corneal nerve wounding often causes abnormalities in the cornea and even blindne...
2024-09

04

Aberrant Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem Cells of a Retinitis Pigmentosa Patient with the PRPF6 Mutation

Pre-mRNA processing factors (PRPFs) are vital components of the spliceosome and ...
2024-09

04

Effect of porcine corneal stromal extract on keratocytes from SMILE-derived lenticules

Propagating large amounts of human corneal stromal cells (hCSCs) in vitro while ...
2024-09

04

KATP Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia

This study aimed to determine the effect of pinacidil, a nonselective KATP chann...
2024-09

04

Characteristics of neural growth and cryopreservation of the dorsal root ganglion using three-dimensional collagen hydrogel culture versus conventional culture

In vertebrates, most somatosensory pathways begin with the activation of dorsal ...
2024-09

04

Dysbiosis and Implication of the Gut Microbiota in Diabetic Retinopathy

The pathogenesis of type 2 diabetes mellitus (T2DM) is commonly associated with ...
2024-09

04

Inhibition of enhancer of zeste homolog 2 prevents corneal myofibroblast transformation in vitro

Corneal fibroblast can be transformed into corneal myofibroblasts by TGF-β1.
2024-09

04

Integrated Analysis of DNA methylation and transcriptome profile to identify key features of age-related macular degeneration

Age-related macular degeneration (AMD) is a common vision-threatening disease. T...
2024-09

04

Mechanotransduction Regulates Reprogramming Enhancement in Adherent 3D Keratocyte Cultures

Suspended spheroid culture using ultralow attachment plates (ULAPs) is reported ...
2024-09

03

Clock Gene Nr1d1 Alleviates Retinal Inflammation Through Repression of Hmga2 in Microglia

Purpose: Retinal inflammation is involved in the pathogenesis of several retinal...
2024-09

03

Tissue‑Specific Gamma‑Flicker Light Noninvasively Ameliorates Retinal Aging

Aging is a risk factor for multiple retinal degeneration diseases. Entraining br...
2024-09

03

Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review

Angiographically silent cystoid macular edema (CME) is a rare complication from ...
2024-09

03

Single-cell RNA sequencing study of retinal immune regulators identified CD47 and CD59a expression in photoreceptors-Implications in subretinal immune regulation

The neuroretina is protected by its own defense system, that is microglia and th...
2024-09

03

Retinal Cell BiologyTranscriptomic Analysis of the DevelopmentalSimilarities and Differences Between the Native Retinaand Retinal Organoids

Purpose: We performed a bioinformatic transcriptome analysis to determine the al...